Boost your UHPLC performance with the 2.1mm Direct-Connect Guard Column – superior protection, refined separation.
The uHPLCs UPLC Direct Connection Guard Column is engineered for ultra-high-performance protection of your analytical columns.
Designed with a direct-connection structure, it minimizes dead volume, eliminates the need for additional fittings, and streamlines system setup — all while extending the lifespan of your main column. Ideal for precision chromatographic analysis in pharmaceuticals, food safety, environmental testing, and biotechnology, the 2.1 mm guard column ensures excellent retention, separation, and reproducibility under high pressure conditions up to 13,000 psi (900 bar).
안내사항 |
가격 기재가 되지 않은 별도 문의 상품인 경우 반드시 '온라인 견적문의' 혹은 '전화 문의' 후 구매 부탁드립니다. 설치/교육 신청의 경우 별도의 연락 후 직접 납품 드립니다. |
Revolutionary 2.1mm UHPLC Direct-Connect Guard Column Hardware
P3K0B 시리즈
Key Features – 2.1 mm UPLC Direct-Connection Guard Column
Direct-Connect Design
No extra joints or tubing required — easy, tool-free installation by hand.
High Pressure Tolerance
Supports up to 13,000 psi (900 bar) for ultra-high performance LC systems.
Low Dead Volume & Back Pressure
Reduces outside-column effects and band broadening for better peak shapes.
Improves Column Life
Acts as a chemical filter to trap contaminants, reducing wear on analytical columns.
Cost-Effective Cartridge Design
Affordable replaceable cartridges reduce long-term consumable cost.
Supports a Variety of Packings
Customizable with multiple reversed-phase and specialty stationary phases:
General-Purpose C18 (L1), 1.8 μm, pH 2–8
100% Water-Compatible C18, 1.8 μm
Water-Compatible + Low pH C18, 1.8 μm, pH 0.5–8
Wide-pH C18, 1.8 μm, pH 1–11
General C8 (L7), Phenyl (L11), SEC (L33/L59), HILIC (L3)
Versatile Applications
Compatible with analyses of:
APIs, natural products, flavonoids, and saponins
Antibiotics, vitamins, hormones
Antibodies, peptides, nucleic acids (SEC)
Polar compounds poorly retained on standard RP columns (HILIC)
Typical Applications of the 2.1 mm UPLC Direct-Connection Guard Column
General-Purpose C18 (L1)
Detection of saponins, flavonoids, polyphenols
Analysis of veterinary drug residues and hormones
Testing traditional Chinese medicinal materials and herbal preparations
100% Water-Compatible C18
Separation of cephalosporin antibiotics
Analysis of water-soluble vitamins (e.g., Vitamin B complex)
Detection of small-molecule drugs like Pefloxacin mesylate and Cimetidine
Pharmaceutical QC for injections and tablets (e.g., Rifaximin, Decitabine, Docetaxel)
100% Water-Compatible + Low pH C18
Quantification of amino acid derivatives and acid-sensitive drugs
Suitable for polar acids like p-Chlorophenylacetic acid and o-Methylsalicylic acid
Used in impurity profiling and stability testing (e.g., Estriol, Nimodipine)
Wide-pH Tolerant C18 (pH 1–11)
Effective for drugs requiring strong pH stability (e.g., Pantoprazole Sodium, Imipenem)
Ideal for formulations prone to strong or irreversible adsorption
Broad-range detection from acidic to alkaline drugs in complex samples
General-Purpose C8 (L7)
Targeting hydrophobic analytes with moderate retention
Ideal for small peptides, immunosuppressants (e.g., Tacrolimus), and herbal mixtures
Applied in the testing of OTC syrups and oral liquids (e.g., Licorice Oral Liquid)
Phenyl Phase (L11)
Specialized for aromatic and π-π interaction compounds
Analysis of botanical extracts and hormone analogs (e.g., Montelukast, Oxytetracycline)
Size Exclusion Chromatography (SEC – L33/L59)
Molecular weight profiling of:
Monoclonal antibodies (mAbs)
Enzymes, nucleic acids, ADCs
Biopharmaceutical development samples
HILIC – Hydrophilic Interaction Chromatography
Retention of very polar, hydrophilic substances
Analysis of substances poorly retained in standard reversed-phase LC
Quantification of glutamine–alanyl–glutamine and other small polar molecules
| Type | Product Code | Application | |
 | UPLC 2.1# Direct Connection Guard Column （Stainless Steel Ferrule） | P3K0B-00272 | UHPLC HPLC Column and LC-MS System |
UPLC 2.1# Direct Connection Guard Column
| Type | Product Code | Characteristic | Particle Size Pore Size | |
 | Reversed Phase | P3X0B-00528 | General TypeC18 | 1.8μm |
| P3X0B-00400 | Pure Water-resistant C18 | 1.8μm | ||
| P3X0B-00401 | Low pH and Pure Water-resistant C18 | 1.8μm | ||
| P3X0B-00402 | Wide pH Range C18 | 1.8μm | ||
| P3X0B-00403 | General Type C8 | 1.8μm | ||
| P3X0B-00404 | Phenyl | 1.8μm | ||
| HILIC | P3X0B-00405 | Hilic-SiO2 | 1.8μm | |
| Reversed Phase | P3X0B-00529 | General Type C18 | 3μm | |
| P3X0B-00530 | Pure Water-resistant C18 | 3μm | ||
| P3X0B-00531 | Low pH and Pure Water-resistant C18 | 3μm | ||
| P3X0B-00532 | Wide pH Range C18 | 3μm | ||
| P3X0B-00533 | General Type C8 | 3μm | ||
| P3X0B-00534 | Phenyl | 3μm | ||
| HILIC | P3X0B-00535 | Hilic-SiO2 | 3μm |
2.1# Direct-Style HPLC Guard Column Holder
| Holder Code | Inner Diameter | Cartridge Dimensions (mm) | Types | Connection Type | Applications | Material |
| P3K0B-00272 | 2.1# | 2.1 × 4.0 | Analytical Guard Column | Direct Connection | UHPLC Column and LC-MS System | 316L Stainless Steel |
2.1# Direct-Style HPLC Guard Column Cartridge
| Cartridge Code | Types | USP | Characteristics | pH Tolerance Range | Applications | Particle Size |
| P3X0B-00528 | Reversed-phase | L1 | General-Purpose C18 | 2–8 | Analysis of saponins, flavonoids, polyphenols, veterinary drug residues, hormones, Chinese medicinal materials, etc. | 1.8μm |
| P3X0B-00400 | Reversed-phase | L1 | 100% Water Compatible C18 | 2–8 | Cephalosporin antibiotics; water-soluble vitamins; Docetaxel; Rifaximin; Aciclovir; Nitroglycerin tablets; etc. | 1.8μm |
| P3X0B-00401 | Reversed-phase | L1 | 100% Water Compatible + Low pH C18 | 0.5–8 | Gentamicin sulfate; Estriol; O-methylsalicylic acid; Nimodipine; Adenosine injection; Aspirin; etc. | 1.8μm |
| P3X0B-00402 | Reversed-phase | L1 | Wide pH C18 | 1–11 | Pantoprazole Sodium; Meropenem; Ranitidine capsules; Moxifloxacin; Octreotide Acetate; etc. | 1.8μm |
| P3X0B-00403 | Reversed-phase | L7 | General-Purpose C8 | 2–8 | Tacrolimus; Clindamycin Phosphate; Compound Licorice Oral Liquid; Rifapentine; etc. | 1.8μm |
| P3X0B-00404 | Reversed-phase | L11 | Phenyl | 2–8 | Montelukast; Oxytetracycline; Garden Radish Seed; Sophorae Fructus Pills; etc. | 1.8μm |
| P3X0B-00405 | HILIC | L3 | Hydrophilic Silica (HILIC-SiO2) | 2–8 | Determination of Glutamine-Alanyl-Glutamine. For substances difficult to retain on RP columns. | 1.8μm |
모바일 환경에서는 표를 좌·우로 스크롤해주세요.
고객센터
배송안내
배송기간
주의사항
안내사항 |
가격 기재가 되지 않은 별도 문의 상품인 경우 반드시 '온라인 견적문의' 혹은 '전화 문의' 후 구매 부탁드립니다. 설치/교육 신청의 경우 별도의 연락 후 직접 납품 드립니다. |
Revolutionary 2.1mm UHPLC Direct-Connect Guard Column Hardware
P3K0B 시리즈
Key Features – 2.1 mm UPLC Direct-Connection Guard Column
Direct-Connect Design
No extra joints or tubing required — easy, tool-free installation by hand.
High Pressure Tolerance
Supports up to 13,000 psi (900 bar) for ultra-high performance LC systems.
Low Dead Volume & Back Pressure
Reduces outside-column effects and band broadening for better peak shapes.
Improves Column Life
Acts as a chemical filter to trap contaminants, reducing wear on analytical columns.
Cost-Effective Cartridge Design
Affordable replaceable cartridges reduce long-term consumable cost.
Supports a Variety of Packings
Customizable with multiple reversed-phase and specialty stationary phases:
General-Purpose C18 (L1), 1.8 μm, pH 2–8
100% Water-Compatible C18, 1.8 μm
Water-Compatible + Low pH C18, 1.8 μm, pH 0.5–8
Wide-pH C18, 1.8 μm, pH 1–11
General C8 (L7), Phenyl (L11), SEC (L33/L59), HILIC (L3)
Versatile Applications
Compatible with analyses of:
APIs, natural products, flavonoids, and saponins
Antibiotics, vitamins, hormones
Antibodies, peptides, nucleic acids (SEC)
Polar compounds poorly retained on standard RP columns (HILIC)
Typical Applications of the 2.1 mm UPLC Direct-Connection Guard Column
General-Purpose C18 (L1)
Detection of saponins, flavonoids, polyphenols
Analysis of veterinary drug residues and hormones
Testing traditional Chinese medicinal materials and herbal preparations
100% Water-Compatible C18
Separation of cephalosporin antibiotics
Analysis of water-soluble vitamins (e.g., Vitamin B complex)
Detection of small-molecule drugs like Pefloxacin mesylate and Cimetidine
Pharmaceutical QC for injections and tablets (e.g., Rifaximin, Decitabine, Docetaxel)
100% Water-Compatible + Low pH C18
Quantification of amino acid derivatives and acid-sensitive drugs
Suitable for polar acids like p-Chlorophenylacetic acid and o-Methylsalicylic acid
Used in impurity profiling and stability testing (e.g., Estriol, Nimodipine)
Wide-pH Tolerant C18 (pH 1–11)
Effective for drugs requiring strong pH stability (e.g., Pantoprazole Sodium, Imipenem)
Ideal for formulations prone to strong or irreversible adsorption
Broad-range detection from acidic to alkaline drugs in complex samples
General-Purpose C8 (L7)
Targeting hydrophobic analytes with moderate retention
Ideal for small peptides, immunosuppressants (e.g., Tacrolimus), and herbal mixtures
Applied in the testing of OTC syrups and oral liquids (e.g., Licorice Oral Liquid)
Phenyl Phase (L11)
Specialized for aromatic and π-π interaction compounds
Analysis of botanical extracts and hormone analogs (e.g., Montelukast, Oxytetracycline)
Size Exclusion Chromatography (SEC – L33/L59)
Molecular weight profiling of:
Monoclonal antibodies (mAbs)
Enzymes, nucleic acids, ADCs
Biopharmaceutical development samples
HILIC – Hydrophilic Interaction Chromatography
Retention of very polar, hydrophilic substances
Analysis of substances poorly retained in standard reversed-phase LC
Quantification of glutamine–alanyl–glutamine and other small polar molecules
| Type | Product Code | Application | |
| UPLC 2.1# Direct Connection Guard Column （Stainless Steel Ferrule） | P3K0B-00272 | UHPLC HPLC Column and LC-MS System |
UPLC 2.1# Direct Connection Guard Column
| Type | Product Code | Characteristic | Particle Size Pore Size | |
| Reversed Phase | P3X0B-00528 | General TypeC18 | 1.8μm |
| P3X0B-00400 | Pure Water-resistant C18 | 1.8μm | ||
| P3X0B-00401 | Low pH and Pure Water-resistant C18 | 1.8μm | ||
| P3X0B-00402 | Wide pH Range C18 | 1.8μm | ||
| P3X0B-00403 | General Type C8 | 1.8μm | ||
| P3X0B-00404 | Phenyl | 1.8μm | ||
| HILIC | P3X0B-00405 | Hilic-SiO2 | 1.8μm | |
| Reversed Phase | P3X0B-00529 | General Type C18 | 3μm | |
| P3X0B-00530 | Pure Water-resistant C18 | 3μm | ||
| P3X0B-00531 | Low pH and Pure Water-resistant C18 | 3μm | ||
| P3X0B-00532 | Wide pH Range C18 | 3μm | ||
| P3X0B-00533 | General Type C8 | 3μm | ||
| P3X0B-00534 | Phenyl | 3μm | ||
| HILIC | P3X0B-00535 | Hilic-SiO2 | 3μm |
2.1# Direct-Style HPLC Guard Column Holder
| Holder Code | Inner Diameter | Cartridge Dimensions (mm) | Types | Connection Type | Applications | Material |
| P3K0B-00272 | 2.1# | 2.1 × 4.0 | Analytical Guard Column | Direct Connection | UHPLC Column and LC-MS System | 316L Stainless Steel |
2.1# Direct-Style HPLC Guard Column Cartridge
| Cartridge Code | Types | USP | Characteristics | pH Tolerance Range | Applications | Particle Size |
| P3X0B-00528 | Reversed-phase | L1 | General-Purpose C18 | 2–8 | Analysis of saponins, flavonoids, polyphenols, veterinary drug residues, hormones, Chinese medicinal materials, etc. | 1.8μm |
| P3X0B-00400 | Reversed-phase | L1 | 100% Water Compatible C18 | 2–8 | Cephalosporin antibiotics; water-soluble vitamins; Docetaxel; Rifaximin; Aciclovir; Nitroglycerin tablets; etc. | 1.8μm |
| P3X0B-00401 | Reversed-phase | L1 | 100% Water Compatible + Low pH C18 | 0.5–8 | Gentamicin sulfate; Estriol; O-methylsalicylic acid; Nimodipine; Adenosine injection; Aspirin; etc. | 1.8μm |
| P3X0B-00402 | Reversed-phase | L1 | Wide pH C18 | 1–11 | Pantoprazole Sodium; Meropenem; Ranitidine capsules; Moxifloxacin; Octreotide Acetate; etc. | 1.8μm |
| P3X0B-00403 | Reversed-phase | L7 | General-Purpose C8 | 2–8 | Tacrolimus; Clindamycin Phosphate; Compound Licorice Oral Liquid; Rifapentine; etc. | 1.8μm |
| P3X0B-00404 | Reversed-phase | L11 | Phenyl | 2–8 | Montelukast; Oxytetracycline; Garden Radish Seed; Sophorae Fructus Pills; etc. | 1.8μm |
| P3X0B-00405 | HILIC | L3 | Hydrophilic Silica (HILIC-SiO2) | 2–8 | Determination of Glutamine-Alanyl-Glutamine. For substances difficult to retain on RP columns. | 1.8μm |
모바일 환경에서는 표를 좌·우로 스크롤해주세요.
고객센터
배송안내
배송기간
주의사항
